PHS Grant-Supported Research with Human Subjects

Human research subjects as human research workers.

Biomedical research involving human subjects has traditionally been treated as a unique endeavor, presenting special risks and demanding special protections. But in several ways, the regulatory scheme governing human subjects research is counter-intuitively less protective than the labor and employment laws applicable to many workers. This Article relies on analogical and legal reasoning to dem...

Supported by an unrestricted educational grant.

Sea Grant RESEARCH NOTES

Co-oxidation is a little understood means of microbial degradation of petroleum hydrocarbons. In co-oxidation, microbes growing on one compound, the growth substrate, are able to oxidize a second · compound, the cosubstrate. This project examines the role of co-oxidation in the degradation of polycyclic aromatic hydrocarbons (PAR's), one of the most recalcitrant petroleum compounds now found in...

Verification of IACUC approval and the just-in-time PHS grant process.

Public Health Service Policy requires institutional animal care and use committees (IACUCs) to review and approve the animal care and use aspects of grant proposals submitted for funding. Initially, submission of verification of approval was required with submission of the proposal; however, in 2002, a ''just-in-time'' (JIT) process was begun to allow submission when it appeared that the propos...

Reforming the regulations governing research with human subjects.

In the wake of the scandal surrounding the Tuskegee syphilis study, Congress established the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research. The commission investigated and made recommendations regarding basic ethical principles guiding research with human beings and the special principles relating to research with fetuses, prisoners, and children...